I've made a list of recommendations for beginners. Note that pretty much all of this is based on my experiences with the Simple, but most of the stuff here could apply to Junior or Plus users.
DO NOT run the nozzle at over 205C for PLA. The PLA will burn stiff inside the nozzle, and no amount of scraping or poking will remove the burnt plastic. If you've already done this, but don't know how to fix it, remove the nozzle from the printer by gripping it snugly with pliers and gently turning it counterclockwise. Then use a blowtorch to burn off the plastic (while holding the nozzle in your pliers).
DO NOT plug the motors in backwards. Yes, I really did this once. It caused the motors to run backwards and make an unholy noise when they reach their mechanical limits and grind against the wood.
DO NOT unplug the printer while it is sending or receiving commands. It causes your Printrboard to go screwy and give you a "commands waiting" dialog in Repetier. To fix: you need to reflash the firmware. Find any post by the user PxT and click the link in his signature line, then download the Firmware Updater app. It's only for Mac, but I think Windows users can use a software called FLIP. The Firmware Updater will guide you through the update process.
DO use painter's tape on the printbed when using PLA. It helps the first layer stick firmly.
DO use a spooling system for your filament. It is bad news when your printer tries to feed a tangle of filament through the drive gear

DO print a filament guide. This keeps the filament from slipping off the drive gear and not getting fed through the hotend.
If anybody else has suggestions, I would encourage you to post them.
I hope this helps you!